Fluorinated Protective Groups for On-Resin Quantification of Solid-Phase Oligosaccharide Synthesis with19F NMR Spectroscopy

ChemBioChem ◽  
2002 ◽  
Vol 3 (12) ◽  
pp. 1266-1269 ◽  
Author(s):  
Mickael Mogemark ◽  
Mikael Elofsson ◽  
Jan Kihlberg
Keyword(s):  
Nmr Spectroscopy ◽  
Solid Phase ◽  
Oligosaccharide Synthesis ◽  
Protective Groups

scholarly journals Acylsulfonamide safety-catch linker: promise and limitations for solid–phase oligosaccharide synthesis

2012 ◽  
Vol 8 ◽  
pp. 2067-2071 ◽  
Author(s):  
Jian Yin ◽  
Steffen Eller ◽  
Mayeul Collot ◽  
Peter H Seeberger
Keyword(s):  
Solid Phase ◽  
Oligosaccharide Synthesis ◽  
Protective Groups

Safety-catch linkers are useful for solid-phase oligosaccharide synthesis as they are orthogonal to many common protective groups. A new acylsulfonamide safety-catch linker was designed, synthesized and employed during glycosylations using an automated carbohydrate synthesizer. The analysis of the cleavage products revealed shortcomings for oligosaccharide synthesis.

The mechanism of formation of 2,7-dimethyl-2,6-octadiene in the synthesis of 3-methylene-7-methyl-1,6-octadiene

1983 ◽  
Vol 48 (7) ◽  
pp. 1864-1866
Author(s):  
Jan Bartoň ◽  
Ivan Kmínek
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Alkali Metal ◽  
Chromatographic Analysis ◽  
Solid Phase ◽  
Reaction Pathway ◽  
Mechanism Of Formation ◽  
Gas Chromatographic Analysis ◽  
C Nmr ◽  
Visual Observations

2,7-Dimethyl-2,6-octadiene is formed in the catalytic solution for the dimerization of 2-methyl-1,3-butadiene to β-myrcene (3-methylene-7-methyl-1,6-octadiene), as revealed by mass spectrometry and 13C NMR spectroscopy. Visual observations together with the results of gas chromatographic analysis of the catalytic solution suggest that the formation of 2,7-dimethyl-2,6-octadiene is associated with the transition of the alkali metal (sodium) from the solid phase into the solution. A reaction pathway is suggested accounting for the formation of 2,7-dimethyl-2,6-octadiene in the system.

Use of controlled pore glass in solid phase oligosaccharide synthesis. Application to the semiautomated synthesis of a glyconucleotide conjugate

1998 ◽  
Vol 39 (14) ◽  
pp. 1953-1956 ◽  
Author(s):  
Matteo Adinolfi ◽  
Gaspare Barone ◽  
Lorenzo De Napoli ◽  
Alfonso Iadonisi ◽  
Gennaro Piccialli
Keyword(s):  
Solid Phase ◽  
Oligosaccharide Synthesis ◽  
Controlled Pore Glass ◽  
Pore Glass

Synthesis of a New Fluoro-Wang Resin for Solid-Phase Reaction Monitoring by19F NMR Spectroscopy

2001 ◽  
Vol 3 (2) ◽  
pp. 177-180 ◽  
Author(s):  
Joseph M. Salvino ◽  
Sharmila Patel ◽  
Mark Drew ◽  
Paul Krowlikowski ◽  
Edward Orton ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Solid Phase ◽  
Solid Phase Reaction ◽  
Phase Reaction ◽  
Reaction Monitoring ◽  
Wang Resin
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